Anti-DCTN2 Polyclonal Antibody
Cat: K008421P
Summary:
| 【Product name】：Anti-DCTN2 Polyclonal Antibody | 【Source】：Rabbit |
| 【Isotype】：IgG | |
| 【Gene ID】：10540 | 【Swiss Prot】：Q13561 |
| 【Species reactivity】：Human,Rat,Mouse | |
| 【Tested applications】：IHC,WB | |
| 【Immunogen】：Recombinant protein of human DCTN2 | |
| 【Storage】：Store at -20℃, avoid freeze/thaw cycles. | |
Background:
This gene encodes a 50-kD subunit of dynactin, a macromolecular complex consisting of 10-11 subunits ranging in size from 22 to 150 kD. Dynactin binds to both microtubules and cytoplasmic dynein. It is involved in a diverse array of cellular functions, including ER-to-Golgi transport, the centripetal movement of lysosomes and endosomes, spindle formation, chromosome movement, nuclear positioning, and axonogenesis. This subunit is present in 4-5 copies per dynactin molecule. It contains three short alpha-helical coiled-coil domains that may mediate association with self or other dynactin subunits.
Verified picture:
Western blot analysis with DCTN2 antibody diluted at 1:1000;Lane: 293T,A375,A549
Immunohistochemistry of paraffin-embedded Human cervical cancer with DCTN2 antibody diluted at 1:25