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Anti-LIG1 Polyclonal Antibody - SAlexa Fluor 532
Cat: K008424P - SAlexa Fluor 532
Summary:
【Product name】:Anti-LIG1 Polyclonal Antibody - SAlexa Fluor 532 【Source】:Rabbit
【Isotype】:IgG 【Purification】:Affinity purification
【Gene ID】:3978 【Swiss Prot】:P18858
【Tested applications】:IHC
【Recommended dilution】:IHC 1:50-150.
【Immunogen】:Recombinant protein of human LIG1
【Public Immunogen Range】:532-801aa
【Storage】:Store at -20℃. Avoid freeze/thaw cycles.
Background:
This gene encodes a member of the ATP-dependent DNA ligase protein family. The encoded protein functions in DNA replication, recombination, and the base excision repair process. Mutations in this gene that lead to DNA ligase I deficiency result in immunodeficiency and increased sensitivity to DNA-damaging agents. Disruption of this gene may also be associated with a variety of cancers. Alternative splicing results in multiple transcript variants.
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