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Anti-KLK6 Polyclonal Antibody
Cat: K008485P
Summary:
【Product name】:Anti-KLK6 Polyclonal Antibody 【Source】:Rabbit
【Isotype】:IgG
【Gene ID】:5653 【Swiss Prot】:Q92876
【Species reactivity】:Human
【Tested applications】:IHC,WB
【Immunogen】:Recombinant protein of human KLK6
【Storage】:Store at -20℃, avoid freeze/thaw cycles.
Background:
Kallikreins are a subgroup of serine proteases having diverse physiological functions. Growing evidence suggests that many kallikreins are implicated in carcinogenesis and some have potential as novel cancer and other disease biomarkers. This gene is one of the fifteen kallikrein subfamily members located in a cluster on chromosome 19. The encoded enzyme is regulated by steroid hormones. In tissue culture, the enzyme has been found to generate amyloidogenic fragments from the amyloid precursor protein, suggesting a potential for involvement in Alzheimer's disease. Multiple alternatively spliced transcript variants that encode different isoforms have been identified for this gene.
Verified picture:
Western blot analysis with KLK6 antibody diluted at 1:1000;Lane: A375,HT29,A431,MCF7,MDA-MB-231,Hela,A549
Immunohistochemistry of paraffin-embedded Human colorectal cancer with KLK6 antibody diluted at 1:20