Background:
NDUFA3 (NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 3), also known as B9, is one of about 45 subunits comprising Complex I of the oxidative phosphorylation electron transport chain. Consisting of 84 amino acids and belonging to the Complex I NDUFA3 subunit family, NDUFA3 functions as an accessory subunit of the multi-protein mitochondrial membrane respiratory chain NADH dehydrogenase complex (known as Complex I). Complex I plays an important role in the transfer of electrons from NADH to the respiratory chain, a process that is essential for cellular respiration.