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Anti-PTPN22 Polyclonal Antibody - SAlexa Fluor 750
Cat: K008529P - SAlexa Fluor 750
Summary:
【Product name】:Anti-PTPN22 Polyclonal Antibody - SAlexa Fluor 750 【Source】:Rabbit
【Isotype】:IgG
【Gene ID】:26191 【Swiss Prot】:Q9Y2R2
【Species reactivity】:Human,Mouse
【Tested applications】:IHC,WB
【Immunogen】:Recombinant protein of human PTPN22
【Storage】:Store at -20℃, avoid freeze/thaw cycles.
Background:
This gene encodes of member of the non-receptor class 4 subfamily of the protein-tyrosine phosphatase family. The encoded protein is a lymphoid-specific intracellular phosphatase that associates with the molecular adapter protein CBL and may be involved in regulating CBL function in the T-cell receptor signaling pathway. Mutations in this gene may be associated with a range of autoimmune disorders including Type 1 Diabetes, rheumatoid arthritis, systemic lupus erythematosus and Graves' disease. Alternatively spliced transcript variants encoding distinct isoforms have been described.
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