Anti-DHCR24 Polyclonal Antibody
Cat: K008546P
Summary:
| 【Product name】：Anti-DHCR24 Polyclonal Antibody | 【Source】：Rabbit |
| 【Isotype】：IgG | |
| 【Gene ID】：1718 | 【Swiss Prot】：Q15392 |
| 【Species reactivity】：Human,Rat,Mouse | |
| 【Tested applications】：IHC,WB | |
| 【Immunogen】：Recombinant protein of human DHCR24 | |
| 【Storage】：Store at -20℃, avoid freeze/thaw cycles. | |
Background:
This gene encodes a flavin adenine dinucleotide (FAD)-dependent oxidoreductase which catalyzes the reduction of the delta-24 double bond of sterol intermediates during cholesterol biosynthesis. The protein contains a leader sequence that directs it to the endoplasmic reticulum membrane. Missense mutations in this gene have been associated with desmosterolosis. Also, reduced expression of the gene occurs in the temporal cortex of Alzheimer disease patients and overexpression has been observed in adrenal gland cancer cells.
Verified picture:
Western blot analysis with DHCR24 antibody diluted at 1:500;Lane: Jurkat,HepG2,HT29,K-562,A375
Immunohistochemistry of paraffin-embedded Human breast cancer with DHCR24 antibody diluted at 1:40