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Anti-MAP3K7 Polyclonal Antibody
Cat: K008561P
Summary:
【Product name】:Anti-MAP3K7 Polyclonal Antibody 【Source】:Rabbit
【Isotype】:IgG
【Gene ID】:6885 【Swiss Prot】:O43318
【Species reactivity】:Human,Rat,Mouse
【Tested applications】:IHC,WB
【Immunogen】:Recombinant protein of human MAP3K7
【Storage】:Store at -20℃, avoid freeze/thaw cycles.
Background:
The protein encoded by this gene is a member of the serine/threonine protein kinase family. This kinase mediates the signaling transduction induced by TGF beta and morphogenetic protein (BMP), and controls a variety of cell functions including transcription regulation and apoptosis. In response to IL-1, this protein forms a kinase complex including TRAF6, MAP3K7P1/TAB1 and MAP3K7P2/TAB2; this complex is required for the activation of nuclear factor kappa B. This kinase can also activate MAPK8/JNK, MAP2K4/MKK4, and thus plays a role in the cell response to environmental stresses. Four alternatively spliced transcript variants encoding distinct isoforms have been reported.
Verified picture:
Western blot analysis with MAP3K7 antibody diluted at 1:1000;Lane: Jurkat,K-562,Hela,A431
Immunohistochemistry of paraffin-embedded Human breast cancer with MAP3K7 antibody diluted at 1:20