Anti-TMED10 Polyclonal Antibody
Cat: K008755P
Summary:
| 【Product name】：Anti-TMED10 Polyclonal Antibody | 【Source】：Rabbit |
| 【Isotype】：IgG | 【Purification】：Affinity purification |
| 【Gene ID】：10972 | 【Swiss Prot】：P49755 |
| 【Tested applications】：WB,IHC | |
| 【Recommended dilution】：WB 1:1000-5000.IHC 1:50-200. | |
| 【Immunogen】：Recombinant protein of human TMED10 | |
| 【Storage】：Store at -20℃. Avoid freeze/thaw cycles. | |
Background:
This gene is a member of the EMP24/GP25L/p24 family and encodes a protein with a GOLD domain. This type I membrane protein is localized to the plasma membrane and golgi cisternae and is involved in vesicular protein trafficking. The protein is also a member of a heteromeric secretase complex and regulates the complex's gamma-secretase activity without affecting its epsilon-secretase activity. Mutations in this gene have been associated with early-onset familial Alzheimer's disease. This gene has a pseudogene on chromosome 8.
Verified picture:
Western blot analysis with TMED10 antibody diluted at 1:3000;Lane: HeLa,Raji,NIH3T3,Mouse pancreas,Mouse liver,Rat lung.
Immunohistochemistry of paraffin-embedded Human lung cancer with TMED10 antibody diluted at 1:100.