Anti-TMED10 Polyclonal Antibody - SAlexa Fluor 350
Cat: K008755P - SAlexa Fluor 350
Summary:
| 【Product name】：Anti-TMED10 Polyclonal Antibody - SAlexa Fluor 350 | 【Source】：Rabbit |
| 【Isotype】：IgG | |
| 【Gene ID】：10972 | 【Swiss Prot】：P49755 |
| 【Species reactivity】：Human,Rat,Mouse | |
| 【Tested applications】：ICC IF | |
| 【Recommended dilution】：ICC 1:50-200. IF 1:50-200 | |
| 【Immunogen】：Recombinant protein of human TMED10 | |
| 【Storage】：Store at -20℃, avoid freeze/thaw cycles. | |
Background:
This gene is a member of the EMP24/GP25L/p24 family and encodes a protein with a GOLD domain. This type I membrane protein is localized to the plasma membrane and golgi cisternae and is involved in vesicular protein trafficking. The protein is also a member of a heteromeric secretase complex and regulates the complex's gamma-secretase activity without affecting its epsilon-secretase activity. Mutations in this gene have been associated with early-onset familial Alzheimer's disease. This gene has a pseudogene on chromosome 8.
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