Anti-GPT Polyclonal Antibody
Cat: K008766P
Summary:
| 【Product name】：Anti-GPT Polyclonal Antibody | 【Source】：Rabbit |
| 【Isotype】：IgG | |
| 【Gene ID】：2875 | 【Swiss Prot】：P24298 |
| 【Species reactivity】：Human | |
| 【Tested applications】：IHC,WB | |
| 【Immunogen】：A synthetic peptide of human GPT | |
| 【Storage】：Store at -20℃, avoid freeze/thaw cycles. | |
Background:
This gene encodes cytosolic alanine aminotransaminase 1 (ALT1); also known as glutamate-pyruvate transaminase 1. This enzyme catalyzes the reversible transamination between alanine and 2-oxoglutarate to generate pyruvate and glutamate and, therefore, plays a key role in the intermediary metabolism of glucose and amino acids. Serum activity levels of this enzyme are routinely used as a biomarker of liver injury caused by drug toxicity, infection, alcohol, and steatosis. A related gene on chromosome 16 encodes a putative mitochondrial alanine aminotransaminase.
Verified picture:
Western blot analysis with GPT antibody diluted at 1:500;Lane: Human liver cancer,Human skin cancer
Immunohistochemistry of paraffin-embedded Human liver cancer with GPT antibody diluted at 1:30