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Anti-KCNA1 Polyclonal Antibody - Biotin
Cat: K008855P - Biotin
Summary:
【Product name】:Anti-KCNA1 Polyclonal Antibody - Biotin 【Source】:Rabbit
【Isotype】:IgG
【Gene ID】:3736 【Swiss Prot】:Q09470
【Species reactivity】:Human,Rat,Mouse
【Tested applications】:WB ELISA IHC ICC
【Recommended dilution】:WB 1:50-200. ELISA 1:100-1000. IHC 1:20-200. ICC 1:50-200. IF 1:50-200
【Immunogen】:A synthetic peptide of human KCNA1
【Storage】:Store at -20℃, avoid freeze/thaw cycles.
Background:
This gene encodes a voltage-gated delayed potassium channel that is phylogenetically related to the Drosophila Shaker channel. The encoded protein has six putative transmembrane segments (S1-S6), and the loop between S5 and S6 forms the pore and contains the conserved selectivity filter motif (GYGD). The functional channel is a homotetramer. The N-terminus of the channel is associated with beta subunits that can modify the inactivation properties of the channel as well as affect expression levels. The C-terminus of the channel is complexed to a PDZ domain protein that is responsible for channel targeting. Mutations in this gene have been associated with myokymia with periodic ataxia (AEMK).
Verified picture: