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Anti-MMP8 Polyclonal Antibody
Cat: K008873P
Summary:
【Product name】:Anti-MMP8 Polyclonal Antibody 【Source】:Rabbit
【Isotype】:IgG
【Gene ID】:4317 【Swiss Prot】:P22894
【Species reactivity】:Human
【Tested applications】:IHC,WB
【Immunogen】:A synthetic peptide of human MMP8
【Storage】:Store at -20℃, avoid freeze/thaw cycles.
Background:
Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMP's are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. However, the enzyme encoded by this gene is stored in secondary granules within neutrophils and is activated by autolytic cleavage. Its function is degradation of type I, II and III collagens. The gene is part of a cluster of MMP genes which localize to chromosome 11q22.3.
Verified picture:
Western blot analysis with MMP8 antibody diluted at 1:1000;Lane: MDA-MB-231,MCF7,A549,HL-60,HepG2,Jurkat
Immunohistochemistry of paraffin-embedded Human colorectal cancer with MMP8 antibody diluted at 1:45