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Anti-FZD1 Polyclonal Antibody - SAlexa Fluor 568
Cat: K008902P - SAlexa Fluor 568
Summary:
【Product name】:Anti-FZD1 Polyclonal Antibody - SAlexa Fluor 568 【Source】:Rabbit
【Isotype】:IgG 【Purification】:Affinity purification
【Gene ID】:8321 【Swiss Prot】:Q9UP38
【Tested applications】:WB
【Recommended dilution】:WB 1:200-1000.
【Immunogen】:A synthetic peptide of human FZD1
【Storage】:Store at -20℃. Avoid freeze/thaw cycles.
Background:
Members of the 'frizzled' gene family encode 7-transmembrane domain proteins that are receptors for Wnt signaling proteins. The FZD1 protein contains a signal peptide, a cysteine-rich domain in the N-terminal extracellular region, 7 transmembrane domains, and a C-terminal PDZ domain-binding motif. The FZD1 transcript is expressed in various tissues. May be involved in transduction and intercellular transmission of polarity information during tissue morphogenesis and/or in differentiated tissues. Activated by Wnt3A, Wnt3, Wnt1 and to a lesser extent Wnt2, but not by Wnt4, Wnt5A, Wnt5B, Wnt6, Wnt7A or Wnt7B.
Verified picture: