Anti-MYSM1 Polyclonal Antibody - SAlexa Fluor 405
Cat: K008928P - SAlexa Fluor 405
Summary:
| 【Product name】：Anti-MYSM1 Polyclonal Antibody - SAlexa Fluor 405 | 【Source】：Rabbit |
| 【Isotype】：IgG | 【Purification】：Affinity purification |
| 【Gene ID】：114803 | 【Swiss Prot】：Q5VVJ2 |
| 【Tested applications】：IHC,WB | |
| 【Recommended dilution】：WB 1:500-2000.IHC 1:50-200. | |
| 【Immunogen】：A synthetic peptide of human MYSM1 | |
| 【Storage】：Store at -20℃. Avoid freeze/thaw cycles. | |
Background:
Metalloprotease that specifically deubiquitinates monoubiquitinated histone H2A, a specific tag for epigenetic transcriptional repression, thereby acting as a coactivator. Preferentially deubiquitinates monoubiquitinated H2A in hyperacetylated nucleosomes. Deubiquitination of histone H2A leads to facilitate the phosphorylation and dissociation of histone H1 from the nucleosome. Acts as a coactivator by participating in the initiation and elongation steps of androgen receptor (AR)-induced gene activation.
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