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Anti-SIPA1 Polyclonal Antibody
Cat: K008947P
Summary:
【Product name】:Anti-SIPA1 Polyclonal Antibody 【Source】:Rabbit
【Isotype】:IgG 【Purification】:Affinity purification
【Gene ID】:6494 【Swiss Prot】:Q96FS4
【Tested applications】:IHC
【Recommended dilution】:IHC 1:25-100.
【Immunogen】:A synthetic peptide of human SIPA1
【Storage】:Store at -20℃. Avoid freeze/thaw cycles.
Background:
The product of this gene is a mitogen induced GTPase activating protein (GAP). It exhibits a specific GAP activity for Ras-related regulatory proteins Rap1 and Rap2, but not for Ran or other small GTPases. This protein may also hamper mitogen-induced cell cycle progression when abnormally or prematurely expressed. It is localized to the perinuclear region. Two alternatively spliced variants encoding the same isoform have been characterized to date.
Verified picture:
Immunohistochemistry of paraffin-embedded Human cervical cancer with SIPA1 antibody diluted at 1:50.