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Anti-AKAP12 Polyclonal Antibody
Cat: K008949P
Summary:
【Product name】:Anti-AKAP12 Polyclonal Antibody 【Source】:Rabbit
【Isotype】:IgG 【Purification】:Affinity purification
【Gene ID】:9590 【Swiss Prot】:Q02952
【Tested applications】:WB,IHC
【Recommended dilution】:WB 1:200-1000. IHC 1:25-100.
【Immunogen】:A synthetic peptide of human AKAP12
【Storage】:Store at -20℃. Avoid freeze/thaw cycles.
Background:
The A-kinase anchor proteins (AKAPs) are a group of structurally diverse proteins, which have the common function of binding to the regulatory subunit of protein kinase A (PKA) and confining the holoenzyme to discrete locations within the cell. This gene encodes a member of the AKAP family. The encoded protein is expressed in endothelial cells, cultured fibroblasts, and osteosarcoma cells. It associates with protein kinases A and C and phosphatase, and serves as a scaffold protein in signal transduction. This protein and RII PKA colocalize at the cell periphery. This protein is a cell growth-related protein. Antibodies to this protein can be produced by patients with myasthenia gravis. Alternative splicing of this gene results in two transcript variants encoding different isoforms.
Verified picture:
Western blot analysis with AKAP12 antibody diluted at 1:500;Lane: HT29,PC-3M-IE8,293T,A549.
Immunohistochemistry of paraffin-embedded Rat brain tissue with AKAP12 antibody diluted at 1:50.