Anti-ACO2 Polyclonal Antibody
Cat: K008961P
Summary:
| 【Product name】：Anti-ACO2 Polyclonal Antibody | 【Source】：Rabbit |
| 【Isotype】：IgG | 【Purification】：Affinity purification |
| 【Gene ID】：50 | 【Swiss Prot】：Q99798 |
| 【Tested applications】：WB,IHC | |
| 【Recommended dilution】：WB 1:500-2000. IHC 1:10-100. | |
| 【Immunogen】：A synthetic peptide of human ACO2 | |
| 【Storage】：Store at -20℃. Avoid freeze/thaw cycles. | |
Background:
The protein encoded by this gene belongs to the aconitase/IPM isomerase family. It is an enzyme that catalyzes the interconversion of citrate to isocitrate via cis-aconitate in the second step of the TCA cycle. This protein is encoded in the nucleus and functions in the mitochondrion. It was found to be one of the mitochondrial matrix proteins that are preferentially degraded by the serine protease 15(PRSS15), also known as Lon protease, after oxidative modification.
Verified picture:
Western blot analysis with ACO2 antibody diluted at 1:1000;Lane: HeLa,K-562,NIH3T3,Mouse brain.
Immunohistochemistry of paraffin-embedded Human breast cancer with ACO2 antibody diluted at 1:50.