Anti-PIAS1 Polyclonal Antibody - SAlexa Fluor 640
Cat: K008988P - SAlexa Fluor 640
Summary:
| 【Product name】：Anti-PIAS1 Polyclonal Antibody - SAlexa Fluor 640 | 【Source】：Rabbit |
| 【Isotype】：IgG | |
| 【Gene ID】：8554 | 【Swiss Prot】：O75925 |
| 【Species reactivity】：Human | |
| 【Tested applications】：WB | |
| 【Immunogen】：A synthetic peptide of human PIAS1 | |
| 【Storage】：Store at -20℃, avoid freeze/thaw cycles. | |
Background:
This gene encodes a member of the mammalian PIAS [protein inhibitor of activated STAT-1 (signal transducer and activator of transcription-1)] family. This member contains a putative zinc-binding motif and a highly acidic region. It inhibits STAT1-mediated gene activation and the DNA binding activity, binds to Gu protein/RNA helicase II/DEAD box polypeptide 21, and interacts with androgen receptor (AR). It functions in testis as a nuclear receptor transcriptional coregulator and may have a role in AR initiation and maintenance of spermatogenesis.?
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