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Anti-STAT2 Polyclonal Antibody - Cy3.5
Cat: K009011P - Cy3.5
Summary:
【Product name】:Anti-STAT2 Polyclonal Antibody - Cy3.5 【Source】:Rabbit
【Isotype】:IgG 【Purification】:Affinity purification
【Gene ID】:6773 【Swiss Prot】:P52630
【Tested applications】:IHC,WB
【Recommended dilution】:WB 1:500-2000.IHC 1:50-200.
【Immunogen】:A synthetic peptide of human STAT2
【Storage】:Store at -20℃. Avoid freeze/thaw cycles.
Background:
The protein encoded by this gene is a member of the STAT protein family. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. In response to interferon (IFN), this protein forms a complex with STAT1 and IFN regulatory factor family protein p48 (ISGF3G), in which this protein acts as a transactivator, but lacks the ability to bind DNA directly. Transcription adaptor P300/CBP (EP300/CREBBP) has been shown to interact specifically with this protein, which is thought to be involved in the process of blocking IFN-alpha response by adenovirus.
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