Anti-IBSP Polyclonal Antibody - SAlexa Fluor 640
Cat: K009021P - SAlexa Fluor 640
Summary:
| 【Product name】：Anti-IBSP Polyclonal Antibody - SAlexa Fluor 640 | 【Source】：Rabbit |
| 【Isotype】：IgG | 【Purification】：Affinity purification |
| 【Gene ID】：3381 | 【Swiss Prot】：P21815 |
| 【Tested applications】：WB,IHC | |
| 【Recommended dilution】：WB 1:500-2000.IHC 1:25-100. | |
| 【Immunogen】：A synthetic peptide of human IBSP | |
| 【Storage】：Store at -20℃. Avoid freeze/thaw cycles. | |
Background:
The protein encoded by this gene is a major structural protein of the bone matrix. It constitutes approximately 12% of the noncollagenous proteins in human bone and is synthesized by skeletal-associated cell types, including hypertrophic chondrocytes, osteoblasts, osteocytes, and osteoclasts. The only extraskeletal site of its synthesis is the trophoblast. This protein binds to calcium and hydroxyapatite via its acidic amino acid clusters, and mediates cell attachment through an RGD sequence that recognizes the vitronectin receptor.
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