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Anti-DUSP2 Polyclonal Antibody
Cat: K009050P
Summary:
【Product name】:Anti-DUSP2 Polyclonal Antibody 【Source】:Rabbit
【Isotype】:IgG 【Purification】:Affinity purification
【Gene ID】:1844 【Swiss Prot】:Q05923
【Tested applications】:IHC,WB
【Recommended dilution】:WB 1:200-1000.IHC 1:25-100.
【Immunogen】:A synthetic peptide of human DUSP2
【Storage】:Store at -20℃. Avoid freeze/thaw cycles.
Background:
The protein encoded by this gene is a member of the dual specificity protein phosphatase subfamily. These phosphatases inactivate their target kinases by dephosphorylating both the phosphoserine/threonine and phosphotyrosine residues. They negatively regulate members of the mitogen-activated protein (MAP) kinase superfamily (MAPK/ERK, SAPK/JNK, p38), which are associated with cellular proliferation and differentiation. Different members of the family of dual specificity phosphatases show distinct substrate specificities for various MAP kinases, different tissue distribution and subcellular localization, and different modes of inducibility of their expression by extracellular stimuli.
Verified picture:
Immunohistochemistry of paraffin-embedded Human thyroid cancer with DUSP2 antibody diluted at 1:50.
Western blot analysis with DUSP2 antibody diluted at 1:500;Lane: HL-60.