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Anti-HIST1H2AB Polyclonal Antibody - Cy3.5
Cat: K009071P - Cy3.5
Summary:
【Product name】:Anti-HIST1H2AB Polyclonal Antibody - Cy3.5 【Source】:Rabbit
【Isotype】:IgG 【Purification】:Affinity Purification
【Gene ID】:3012/8335 【Swiss Prot】:P04908
【Tested applications】:WB,IHC
【Recommended dilution】:WB 1:200-1000. IHC 1:10-100.
【Immunogen】:A synthetic peptide of human HIST1H2AB
【Storage】:Store at -20℃. Avoid freeze/thaw cycles.
Background:
Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. This structure consists of approximately 146 bp of DNA wrapped around a nucleosome, an octamer composed of pairs of each of the four core histones (H2A, H2B, H3, and H4). The chromatin fiber is further compacted through the interaction of a linker histone, H1, with the DNA between the nucleosomes to form higher order chromatin structures. This gene is intronless and encodes a member of the histone H2A family. Transcripts from this gene lack polyA tails; instead, they contain a palindromic termination element. This gene is found in the large histone gene cluster on chromosome 6p22-p21.3.
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