Anti-PDE4A Polyclonal Antibody
Cat: K009139P
Summary:
| 【Product name】：Anti-PDE4A Polyclonal Antibody | 【Source】：Rabbit |
| 【Isotype】：IgG | 【Purification】：Affinity purification |
| 【Gene ID】：5141 | 【Swiss Prot】：P27815 |
| 【Tested applications】：WB,IHC | |
| 【Recommended dilution】：WB 1:500-2000. IHC 1:30-150. | |
| 【Immunogen】：A synthetic peptide of human PDE4A | |
| 【Storage】：Store at -20℃. Avoid freeze/thaw cycles. | |
Background:
The protein encoded by this gene belongs to the cyclic nucleotide phosphodiesterase (PDE) family, and PDE4 subfamily. This PDE hydrolyzes the second messenger, cAMP, which is a regulator and mediator of a number of cellular responses to extracellular signals. Thus, by regulating the cellular concentration of cAMP, this protein plays a key role in many important physiological processes. Alternatively spliced transcript variants encoding different isoforms have been described for this gene.
Verified picture:
Immunohistochemistry of paraffin-embedded Human colorectal cancer with PDE4A antibody diluted at 1:100.
Western blot analysis with PDE4A antibody diluted at 1:1000;Lane: HeLa,HMC-1,K-562,THP-1.