Anti-PPOX Polyclonal Antibody
Cat: K009147P
Summary:
| 【Product name】：Anti-PPOX Polyclonal Antibody | 【Source】：Rabbit |
| 【Isotype】：IgG | 【Purification】：Affinity purification |
| 【Gene ID】：5498 | 【Swiss Prot】：P50336 |
| 【Tested applications】：IHC,WB | |
| 【Recommended dilution】：WB 1:1000-5000. IHC 1:30-150. | |
| 【Immunogen】：A synthetic peptide of human PPOX | |
| 【Storage】：Store at -20℃. Avoid freeze/thaw cycles. | |
Background:
This gene encodes the penultimate enzyme of heme biosynthesis, which catalyzes the 6-electron oxidation of protoporphyrinogen IX to form protoporphyrin IX. Mutations in this gene cause variegate porphyria, an autosomal dominant disorder of heme metabolism resulting from a deficiency in protoporphyrinogen oxidase, an enzyme located on the inner mitochondrial membrane. Alternatively spliced transcript variants encoding the same protein have been identified.
Verified picture:
Immunohistochemistry of paraffin-embedded Human breast cancer with PPOX antibody diluted at 1:100.
Western blot analysis with PPOX antibody diluted at 1:3000;Lane: K-562,293T,HepG2.