Anti-RRAS Polyclonal Antibody
Cat: K009165P
Summary:
| 【Product name】：Anti-RRAS Polyclonal Antibody | 【Source】：Rabbit |
| 【Isotype】：IgG | |
| 【Gene ID】：6237 | 【Swiss Prot】：P10301 |
| 【Species reactivity】：Human,Rat,Mouse | |
| 【Tested applications】：WB,IHC | |
| 【Immunogen】：A synthetic peptide of human RRAS | |
| 【Storage】：Store at -20℃, avoid freeze/thaw cycles. | |
Background:
The R-Ras protein has been shown to interact with the Bcl-2 gene product involved in a signaling pathway that intervenes with apoptosis. Positions 38 and 87 (analogous to positions 12 and 61 in H-Ras) mutants of R-Ras have been shown to be capable of activating oncogenic function. Data has been obtained indicating that R-Ras may exert its biological effect by means of modulating the activity of the Raf-1 kinase on its direct downstream effectors.
Verified picture:
Western blot analysis with RRAS antibody diluted at 1:1000;Lane: A431,HT-29,PC-3M-IE8
Immunohistochemistry of paraffin-embedded Human cervical cancer with RRAS antibody diluted at 1:25