Anti-RRAS Polyclonal Antibody - Cy3
Cat: K009165P - Cy3
Summary:
| 【Product name】：Anti-RRAS Polyclonal Antibody - Cy3 | 【Source】：Rabbit |
| 【Isotype】：IgG | |
| 【Gene ID】：6237 | 【Swiss Prot】：P10301 |
| 【Species reactivity】：Human,Rat,Mouse | |
| 【Tested applications】：ICC IF | |
| 【Recommended dilution】：ICC 1:50-200. IF 1:50-200 | |
| 【Immunogen】：A synthetic peptide of human RRAS | |
| 【Storage】：Store at -20℃, avoid freeze/thaw cycles. | |
Background:
The R-Ras protein has been shown to interact with the Bcl-2 gene product involved in a signaling pathway that intervenes with apoptosis. Positions 38 and 87 (analogous to positions 12 and 61 in H-Ras) mutants of R-Ras have been shown to be capable of activating oncogenic function. Data has been obtained indicating that R-Ras may exert its biological effect by means of modulating the activity of the Raf-1 kinase on its direct downstream effectors.
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