Anti-SESN1 Polyclonal Antibody - SAlexa Fluor 568
Cat: K009169P - SAlexa Fluor 568
Summary:
| 【Product name】：Anti-SESN1 Polyclonal Antibody - SAlexa Fluor 568 | 【Source】：Rabbit |
| 【Isotype】：IgG | |
| 【Gene ID】：27244 | 【Swiss Prot】：Q9Y6P5 |
| 【Species reactivity】：Human,Mouse | |
| 【Tested applications】：WB | |
| 【Immunogen】：A synthetic peptide of human SESN1 | |
| 【Storage】：Store at -20℃, avoid freeze/thaw cycles. | |
Background:
This gene encodes a member of the sestrin family. Sestrins are induced by the p53 tumor suppressor protein and play a role in the cellular response to DNA damage and oxidative stress. The encoded protein mediates p53 inhibition of cell growth by activating AMP-activated protein kinase, which results in the inhibition of the mammalian target of rapamycin protein. The encoded protein also plays a critical role in antioxidant defense by regenerating overoxidized peroxiredoxins, and the expression of this gene is a potential marker for exposure to radiation.?
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