Anti-SIK1 Polyclonal Antibody
Cat: K009180P
Summary:
| 【Product name】：Anti-SIK1 Polyclonal Antibody | 【Source】：Rabbit |
| 【Isotype】：IgG | 【Purification】：Affinity purification |
| 【Gene ID】：102724428/150094 | 【Swiss Prot】：P57059 |
| 【Tested applications】：IHC,WB | |
| 【Recommended dilution】：WB 1:500-2000.IHC 1:25-100. | |
| 【Immunogen】：A synthetic peptide of human SIK1 | |
| 【Storage】：Store at -20℃. Avoid freeze/thaw cycles. | |
Background:
SIK1 (salt-inducible kinase 1), also known as SNF1LK or MSK, is a 783 amino acid protein that contains one UBA domain and one protein kinase domain and belongs to the Ser/Thr protein kinase family. Localized to both the nucleus and the cytoplasm, SIK1 uses magnesium as a cofactor to catalyze the ATP-dependent phosphorylation of target proteins and is thought to be important for the early stages of skeletal muscle growth and myocardial cell differentiation. Additionally, SIK1 has a potential role in regulation of the G2/M cell cycle transition, as well as in inhibitory control of CREB protein function.
Verified picture:
Immunohistochemistry of paraffin-embedded Human colorectal cancer with SIK1 antibody diluted at 1:50.
Western blot analysis with SIK1 antibody diluted at 1:1000;Lane: Jurkat,PC-3M-IE8.