Anti-STARD4 Polyclonal Antibody
Cat: K009186P
Summary:
| 【Product name】：Anti-STARD4 Polyclonal Antibody | 【Source】：Rabbit |
| 【Isotype】：IgG | 【Purification】：Affinity purification |
| 【Gene ID】：134429 | 【Swiss Prot】：Q96DR4 |
| 【Tested applications】：IHC,WB | |
| 【Recommended dilution】：WB 1:200-1000.IHC 1:25-100. | |
| 【Immunogen】：A synthetic peptide of human STARD4 | |
| 【Storage】：Store at -20℃. Avoid freeze/thaw cycles. | |
Background:
Cholesterol homeostasis is regulated, at least in part, by sterol regulatory element (SRE)-binding proteins (e.g., SREBP1; MIM 184756) and by liver X receptors (e.g., LXRA; MIM 602423). Upon sterol depletion, LXRs are inactive and SREBPs are cleaved, after which they bind promoter SREs and activate genes involved in cholesterol biosynthesis and uptake. Sterol transport is mediated by vesicles or by soluble protein carriers, such as steroidogenic acute regulatory protein (STAR; MIM 600617). STAR is homologous to a family of proteins containing a 200- to 210-amino acid STAR-related lipid transfer (START) domain, including STARD4 (Soccio et al., 2002 [PubMed 12011452]).
Verified picture:
Immunohistochemistry of paraffin-embedded Human gastric cancer with STARD4 antibody diluted at 1:50.
Western blot analysis with STARD4 antibody diluted at 1:500;Lane: Human fatal liver,Mouse liver.