Anti-TM7SF2 Polyclonal Antibody - SAlexa Fluor 640
Cat: K009193P - SAlexa Fluor 640
Summary:
| 【Product name】：Anti-TM7SF2 Polyclonal Antibody - SAlexa Fluor 640 | 【Source】：Rabbit |
| 【Isotype】：IgG | |
| 【Gene ID】：7108 | 【Swiss Prot】：O76062 |
| 【Species reactivity】：Human,Mouse | |
| 【Tested applications】：IHC,WB | |
| 【Immunogen】：A synthetic peptide of human TM7SF2 | |
| 【Storage】：Store at -20℃, avoid freeze/thaw cycles. | |
Background:
Transmembrane 7 superfamily member 2 (TM7SF2, Sterol C14-reductase, 3beta-hydroxysterol Delta-reductase) is a 418 amino acid gene product that belongs to the ERG4/ERG24 family. TM7SF2 is a seven pass transmembrane protein that can localize to the membrane of the endoplasmic reticulum. TM7SF2 is involved in the conversion of lanosterol to cholesterol and, specifically, catalyzes the NADPH dependant reduction of 4,4-dimethyl-5-alpha-cholesta-8,14,24-trien-3-beta-ol to 4,4-dimethyl-5-alpha-cholesta-8,24-dien-3-beta-ol and NADP+.
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