Anti-VMP1 Polyclonal Antibody
Cat: K009195P
Summary:
| 【Product name】：Anti-VMP1 Polyclonal Antibody | 【Source】：Rabbit |
| 【Isotype】：IgG | 【Purification】：Affinity purification |
| 【Gene ID】：81671 | 【Swiss Prot】：Q96GC9 |
| 【Tested applications】：IHC,WB | |
| 【Recommended dilution】：WB 1:500-2000.IHC 1:25-100. | |
| 【Immunogen】：A synthetic peptide of human VMP1 | |
| 【Storage】：Store at -20℃. Avoid freeze/thaw cycles. | |
Background:
VMP1 (Vacuole membrane protein 1), is a 406 amino acid multi-pass membrane protein that localizes to the endoplasmic reticulum-golgi intermediate compartment membrane. Stress-induced protein that, when overexpressed, promotes formation of intracellular vacuoles followed by cell death. May be involved in the cytoplasmic vacuolization of acinar cells during the early stage of acute pancreatitis. Plays a role in the initial stages of the autophagic process through its interaction with BECN1 (By similarity). Involved in cell-cell adhesion.
Verified picture:
Immunohistochemistry of paraffin-embedded Human esophageal cancer with VMP1 antibody diluted at 1:50.
Western blot analysis with VMP1 antibody diluted at 1:1000;Lane: MCF7.