Anti-CFH Polyclonal Antibody
Cat: K009274P
Summary:
| 【Product name】：Anti-CFH Polyclonal Antibody | 【Source】：Rabbit |
| 【Isotype】：IgG | 【Purification】：Affinity purification |
| 【Gene ID】：3075 | 【Swiss Prot】：P08603 |
| 【Tested applications】：WB | |
| 【Recommended dilution】：WB 1:200-1000. | |
| 【Immunogen】：A synthetic peptide of human CFH | |
| 【Public Immunogen Range】：1181-1216aa | |
| 【Storage】：Store at -20℃. Avoid freeze/thaw cycles. | |
Background:
This gene is a member of the Regulator of Complement Activation (RCA) gene cluster and encodes a protein with twenty short consensus repeat (SCR) domains. This protein is secreted into the bloodstream and has an essential role in the regulation of complement activation, restricting this innate defense mechanism to microbial infections. Mutations in this gene have been associated with hemolytic-uremic syndrome (HUS) and chronic hypocomplementemic nephropathy. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.
Verified picture:
Western blot analysis with CFH antibody diluted at 1:500;Lane: Human bladder cancer.