Anti-NF1 Polyclonal Antibody
Cat: K009302P
Summary:
| 【Product name】：Anti-NF1 Polyclonal Antibody | 【Source】：Rabbit |
| 【Isotype】：IgG | |
| 【Gene ID】：4763 | 【Swiss Prot】：P21359 |
| 【Species reactivity】：Human,Rat,Mouse | |
| 【Tested applications】：IHC | |
| 【Immunogen】：A synthetic peptide of human NF1 | |
| 【Storage】：Store at -20℃, avoid freeze/thaw cycles. | |
Background:
This gene product appears to function as a negative regulator of the ras signal transduction pathway. Mutations in this gene have been linked to neurofibromatosis type 1, juvenile myelomonocytic leukemia and Watson syndrome. The mRNA for this gene is subject to RNA editing (CGA>UGA->Arg1306Term) resulting in premature translation termination. Alternatively spliced transcript variants encoding different isoforms have also been described for this gene.
Verified picture:
Immunohistochemistry of paraffin-embedded Human colorectal cancer with NF1 antibody diluted at 1:25