Anti-CDC42BPA Polyclonal Antibody
Cat: K009322P
Summary:
| 【Product name】：Anti-CDC42BPA Polyclonal Antibody | 【Source】：Rabbit |
| 【Isotype】：IgG | 【Purification】：Affinity purification |
| 【Gene ID】：8476 | 【Swiss Prot】：Q5VT25 |
| 【Tested applications】：IHC,WB | |
| 【Recommended dilution】：WB 1:500-2000.IHC 1:30-150 | |
| 【Immunogen】：A synthetic peptide of human CDC42BPA | |
| 【Storage】：Store at -20℃. Avoid freeze/thaw cycles. | |
Background:
The protein encoded by this gene is a member of the Serine/Threonine protein kinase family. This kinase contains multiple functional domains. Its kinase domain is highly similar to that of the myotonic dystrophy protein kinase (DMPK). This kinase also contains a Rac interactive binding (CRIB) domain, and has been shown to bind CDC42. It may function as a CDC42 downstream effector mediating CDC42 induced peripheral actin formation, and promoting cytoskeletal reorganization. Multiple alternatively spliced transcript variants have been described, and the full-length nature of two of them has been reported.
Verified picture:
Western blot analysis with CDC42BPA antibody diluted at 1:1000;Lane: SH-SY5Y,Jurkat,HT-29,SW480,K-562,A431.
Immunohistochemistry of paraffin-embedded Human colorectal cancer with CDC42BPA antibody diluted at 1:100.