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Anti-CDC42BPA Polyclonal Antibody
Cat: K009322P
Summary:
【Product name】:Anti-CDC42BPA Polyclonal Antibody 【Source】:Rabbit
【Isotype】:IgG
【Gene ID】:8476 【Swiss Prot】:Q5VT25
【Species reactivity】:Human,Rat,Mouse
【Tested applications】:IHC,WB
【Immunogen】:A synthetic peptide of human CDC42BPA
【Storage】:Store at -20℃, avoid freeze/thaw cycles.
Background:
The protein encoded by this gene is a member of the Serine/Threonine protein kinase family. This kinase contains multiple functional domains. Its kinase domain is highly similar to that of the myotonic dystrophy protein kinase (DMPK). This kinase also contains a Rac interactive binding (CRIB) domain, and has been shown to bind CDC42. It may function as a CDC42 downstream effector mediating CDC42 induced peripheral actin formation, and promoting cytoskeletal reorganization. Multiple alternatively spliced transcript variants have been described, and the full-length nature of two of them has been reported.
Verified picture:
Western blot analysis with CDC42BPA antibody diluted at 1:1000;Lane: SH-SY5Y,Jurkat,HT-29,SW480,K-562,A431
Immunohistochemistry of paraffin-embedded Human colorectal cancer with CDC42BPA antibody diluted at 1:45