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Anti-WDFY2 Polyclonal Antibody - SAlexa Fluor 350
Cat: K008620P - SAlexa Fluor 350
Summary:
【Product name】:Anti-WDFY2 Polyclonal Antibody - SAlexa Fluor 350 【Source】:Rabbit
【Isotype】:IgG
【Gene ID】:115825 【Swiss Prot】:Q96P53
【Species reactivity】:Human,Mouse
【Tested applications】:ICC IF
【Recommended dilution】:ICC 1:50-200. IF 1:50-200
【Immunogen】:Recombinant protein of human WDFY2
【Storage】:Store at -20℃, avoid freeze/thaw cycles.
Background:
WD repeat and FYVE domain-containing protein 2 (WDFY2), also known as WDF2 and ZFYVE22, is a 400 amino acid protein that localizes to a set of small endosomes that are found within 100 nm from the plasma membrane. Highly conserved between species, WDFY2 consists of one FYVE-type zinc finger and seven WD repeats. The FYVE domain is a cysteine-rich domain of about 70 amino acids. Its primary role is to target signal-transducing proteins to cell membranes through binding to the membrane lipid phosphatidylinositol-3-phosphate with high specificity. WD-repeats are generally found in clusters of seven. They have no intrinsic catalytic activity, but they serve as a platform for protein-protein interactions. WDFY2 is suspected to play a critical role in the endocytic pathway.
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