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Anti-VTI1A Polyclonal Antibody
Cat: K008625P
Summary:
【Product name】:Anti-VTI1A Polyclonal Antibody 【Source】:Rabbit
【Isotype】:IgG
【Gene ID】:143187 【Swiss Prot】:Q96AJ9
【Species reactivity】:Human,Mouse
【Tested applications】:IHC,WB
【Immunogen】:Recombinant protein of human VTI1A
【Storage】:Store at -20℃, avoid freeze/thaw cycles.
Background:
The protein encoded by this gene is a member of the family of soluble N-ethylmaleimide-sensitive fusion protein-attachment protein receptors (SNAREs) that function in intracellular trafficking. This family member is involved in vesicular transport between endosomes and the trans-Golgi network. It is a vesicle-associated SNARE (v-SNARE) that interacts with target membrane SNAREs (t-SNAREs). Polymorphisms in this gene have been associated with binocular function, and also with susceptibility to colorectal and lung cancers. A recurrent rearrangement has been found between this gene and the transcription factor 7-like 2 (TCF7L2) gene in colorectal cancers. Alternative splicing results in multiple transcript variants.
Verified picture:
Western blot analysis with VTI1A antibody diluted at 1:1000;Lane: HepG2,Hela,Jurkat,MDA-MB-231,MCF7,SH-SY5Y
Immunohistochemistry of paraffin-embedded Human breast cancer with VTI1A antibody diluted at 1:30