Anti-POR Polyclonal Antibody - Biotin
Cat: K008672P - Biotin
Summary:
| 【Product name】：Anti-POR Polyclonal Antibody - Biotin | 【Source】：Rabbit |
| 【Isotype】：IgG | |
| 【Gene ID】：5447 | 【Swiss Prot】：P16435 |
| 【Species reactivity】：Human,Rat,Mouse | |
| 【Tested applications】：WB ELISA IHC ICC | |
| 【Recommended dilution】：WB 1:50-200. ELISA 1:100-1000. IHC 1:20-200. ICC 1:50-200. IF 1:50-200 | |
| 【Immunogen】：Recombinant protein of human POR | |
| 【Storage】：Store at -20℃, avoid freeze/thaw cycles. | |
Background:
This gene encodes an endoplasmic reticulum membrane oxidoreductase with an FAD-binding domain and a flavodoxin-like domain. The protein binds two cofactors, FAD and FMN, which allow it to donate electrons directly from NADPH to all microsomal P450 enzymes. Mutations in this gene have been associated with various diseases, including apparent combined P450C17 and P450C21 deficiency, amenorrhea and disordered steroidogenesis, congenital adrenal hyperplasia and Antley-Bixler syndrome.
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