Anti-UBXN1 Polyclonal Antibody - SAlexa Fluor 633
Cat: K008682P - SAlexa Fluor 633
Summary:
| 【Product name】：Anti-UBXN1 Polyclonal Antibody - SAlexa Fluor 633 | 【Source】：Rabbit |
| 【Isotype】：IgG | 【Purification】：Affinity purification |
| 【Gene ID】：51035 | 【Swiss Prot】：Q04323 |
| 【Tested applications】：WB,IHC | |
| 【Recommended dilution】：WB 1:500-2000. IHC 1:10-100. | |
| 【Immunogen】：Recombinant protein of human UBXN1 | |
| 【Storage】：Store at -20℃. Avoid freeze/thaw cycles. | |
Background:
Ubiquitin-binding protein that interacts with the BRCA1-BARD1 heterodimer, and regulates its activity. Specifically binds 'Lys-6'-linked polyubiquitin chains. Interaction with autoubiquitinated BRCA1, leads to inhibit the E3 ubiquitin-protein ligase activity of the BRCA1-BARD1 heterodimer. Component of a complex required to couple deglycosylation and proteasome-mediated degradation of misfolded proteins in the endoplasmic reticulum that are retrotranslocated in the cytosol.
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