Anti-Rab14 (7A6) Monoclonal Antibody - SAlexa Fluor 488
Cat: K009409M - SAlexa Fluor 488
Summary:
| 【Product name】：Anti-Rab14 (7A6) Monoclonal Antibody - SAlexa Fluor 488 | 【Source】：Mouse |
| 【Isotype】：IgG | |
| 【Gene ID】：51552 | 【Swiss Prot】：P61106 |
| 【Species reactivity】：Human | |
| 【Tested applications】：FC ICC IF | |
| 【Recommended dilution】：Flow-Cyt 1:50-200. ICC 1:50-200. IF 1:50-200 | |
| 【Immunogen】：Recombinant protein of human RAB14 | |
| 【Storage】：Store at -20℃. Avoid freeze / thaw cycles. | |
Background:
Involved in membrane trafficking between the Golgi complex and endosomes during early embryonic development. Regulates the Golgi to endosome transport of FGFR-containing vesicles during early development, a key process for developing basement membrane and epiblast and primitive endoderm lineages during early postimplantation development. May act by modulating the kinesin KIF16B-cargo association to endosomes (By similarity). Regulates, together with its guanine nucleotide exchange factor DENND6A, the specific endocytic transport of ADAM10, N- cadherin/CDH2 shedding and cell-cell adhesion.
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