下载
Anti-PSMC6 Polyclonal Antibody
Cat: K107281P
Summary:
【Product name】:Anti-PSMC6 Polyclonal Antibody 【Source】:Rabbit
【Isotype】:IgG
【Gene ID】:5706 【Swiss Prot】:P62333
【Species reactivity】:Human,Rat,Mouse
【Tested applications】:WB,IHC
【Immunogen】:A synthetic peptide of human PSMC6
【Storage】:Store at -20℃, avoid freeze/thaw cycles.
Background:
Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair. PSMC6 belongs to the heterohexameric ring of AAA (ATPases associated with diverse cellular activities) proteins that unfolds ubiquitinated target proteins that are concurrently translocated into a proteolytic chamber and degraded into peptides.
Verified picture:
Western blot analysis with PSMC6 antibody diluted at 1:1000;Lane: 293T,SH-SY5Y,Mouse liver,Mouse kidney,Mouse brain.
Immunohistochemistry of paraffin-embedded Human esophageal cancer with PSMC6 antibody diluted at 1:200.
Immunohistochemistry of paraffin-embedded Human prostate cancer with PSMC6 antibody diluted at 1:200.