Anti-Gli3 Polyclonal Antibody - FITC
Cat: K107300P - FITC
Summary:
| 【Product name】：Anti-Gli3 Polyclonal Antibody - FITC | 【Source】：Rabbit |
| 【Isotype】：IgG | |
| 【Gene ID】：2737 | 【Swiss Prot】：P10071 |
| 【Species reactivity】：Human,Chicken,Mouse | |
| 【Tested applications】：ICC IF | |
| 【Recommended dilution】：Flow-Cyt 1:50-200. ICC 1:50-200. IF 1:50-200 | |
| 【Immunogen】：A synthetic peptide of human Gli3 | |
| 【Storage】：Store at -20℃, avoid freeze/thaw cycles. | |
Background:
This gene encodes a protein which belongs to the C2H2-type zinc finger proteins subclass of the Gli family. They are characterized as DNA-binding transcription factors and are mediators of Sonic hedgehog (Shh) signaling. The protein encoded by this gene localizes in the cytoplasm and activates patched Drosophila homolog (PTCH) gene expression. It is also thought to play a role during embryogenesis. Mutations in this gene have been associated with several diseases, including Greig cephalopolysyndactyly syndrome, Pallister-Hall syndrome, preaxial polydactyly type IV, and postaxial polydactyly types A1 and B.
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