Anti-DDRGK1 Polyclonal Antibody
Cat: K107350P
Summary:
| 【Product name】：Anti-DDRGK1 Polyclonal Antibody | 【Source】：Rabbit |
| 【Isotype】：IgG | 【Purification】：Octanoic acid-ammonium sulfate precipitation |
| 【Gene ID】：65992 | 【Swiss Prot】：Q96HY6 |
| 【Tested applications】：WB | |
| 【Recommended dilution】：WB 1:5000-8000. | |
| 【Immunogen】：Recombinant protein of human DDRGK1 | |
| 【Public Immunogen Range】：1-314aa | |
| 【Storage】：Store at -20℃. Avoid freeze/thaw cycles. | |
Background:
Protein which interacts with the E3 UFM1-protein ligase UFL1 and one of its substrates TRIP4 and is required for TRIP4 ufmylation. Through TRIP4 ufmylation may regulate nuclear receptors-mediated transcription (PubMed:25219498). May play a role in NF-kappa-B-mediated transcription through regulation of the phosphorylation and the degradation of NFKBIA, the inhibitor of NF-kappa-B (PubMed:23675531). May also play a role in the cellular response to endoplasmic reticulum stress (By similarity). Plays a role in cartilage development through SOX9, inhibiting the ubiquitin-mediated proteasomal degradation of this transcriptional regulator (PubMed:28263186).
Verified picture:
Western blot analysis with DDRGK1 antibody diluted at 1:6000;Lane: HeLa,HepG2.