Anti-ARRDC3 Polyclonal Antibody - SAlexa Fluor 532
Cat: K107394P - SAlexa Fluor 532
Summary:
| 【Product name】：Anti-ARRDC3 Polyclonal Antibody - SAlexa Fluor 532 | 【Source】：Rabbit |
| 【Isotype】：IgG | 【Purification】：Affinity purification |
| 【Gene ID】：57561 | 【Swiss Prot】：Q96B67 |
| 【Tested applications】：WB,IHC | |
| 【Recommended dilution】：WB 1:5000-8000. IHC 1:50-200. | |
| 【Immunogen】：Recombinant protein of human ARRDC3 | |
| 【Public Immunogen Range】：1-414aa | |
| 【Storage】：Store at -20℃. Avoid freeze/thaw cycles. | |
Background:
Adapter protein that plays a role in regulating cell-surface expression of adrenergic receptors and probably also other G protein-coupled receptors (PubMed:20559325, PubMed:21982743, PubMed:23208550). Plays a role in NEDD4-mediated ubiquitination and endocytosis af activated ADRB2 and subsequent ADRB2 degradation (PubMed:20559325, PubMed:23208550). May recruit NEDD4 to ADRB2 (PubMed:20559325). Alternatively, may function as adapter protein that does not play a major role in recruiting NEDD4 to ADRB2, but rather plays a role in a targeting ADRB2 to endosomes (PubMed:23208550).
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