Anti-IVD Polyclonal Antibody
Cat: K107398P
Summary:
| 【Product name】：Anti-IVD Polyclonal Antibody | 【Source】：Rabbit |
| 【Isotype】：IgG | 【Purification】：Affinity purification |
| 【Gene ID】：3712 | 【Swiss Prot】：P26440 |
| 【Tested applications】：WB,IHC | |
| 【Recommended dilution】：WB 1:5000-8000. IHC 1:50-200. | |
| 【Immunogen】：Recombinant protein of human IVD | |
| 【Public Immunogen Range】：1-426aa | |
| 【Storage】：Store at -20℃. Avoid freeze/thaw cycles. | |
Background:
Isovaleryl-CoA dehydrogenase (IVD) is a mitochondrial matrix enzyme that catalyzes the third step in leucine catabolism. The genetic deficiency of IVD results in an accumulation of isovaleric acid, which is toxic to the central nervous system and leads to isovaleric acidemia. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
Verified picture:
Western blot analysis with IVD antibody diluted at 1:6000;Lane: Mouse lung,Mouse heart,Mouse liver.
Immunohistochemistry of paraffin-embedded Human liver cancer with IVD antibody diluted at 1:100.