Anti-CP110 Polyclonal Antibody
Cat: K107060P
Summary:
| 【Product name】：Anti-CP110 Polyclonal Antibody | 【Source】：Rabbit |
| 【Isotype】：IgG | |
| 【Gene ID】：9738 | 【Swiss Prot】：O43303 |
| 【Species reactivity】：Human | |
| 【Tested applications】：IHC | |
| 【Immunogen】：Recombinant protein of human CP110 | |
| 【Storage】：Store at -20℃, avoid freeze/thaw cycles. | |
Background:
Necessary for centrosome duplication at different stages of procentriole formation. Acts as a key negative regulator of ciliogenesis in collaboration with CEP97 by capping the mother centriole thereby preventing cilia formation. Also involved in promoting ciliogenesis. May play a role in the assembly of the mother centriole subdistal appendages thereby effecting the fusion of recycling endosomes to basal bodies during cilia formation. Required for correct spindle formation and has a role in regulating cytokinesis and genome stability via cooperation with CALM1 and CETN2.
Verified picture:
Immunohistochemistry of paraffin-embedded Human Renal cancer with CP110 antibody diluted at 1:100.