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Anti-CP110 Polyclonal Antibody - Cy3.5
Cat: K107060P - Cy3.5
Summary:
【Product name】:Anti-CP110 Polyclonal Antibody - Cy3.5 【Source】:Rabbit
【Isotype】:IgG 【Purification】:Affinity purification
【Gene ID】:9738 【Swiss Prot】:O43303
【Tested applications】:IHC
【Recommended dilution】:IHC 1:50-200.
【Immunogen】:Recombinant protein of human CP110
【Public Immunogen Range】:1-337aa
【Storage】:Store at -20℃. Avoid freeze/thaw cycles.
Background:
Necessary for centrosome duplication at different stages of procentriole formation. Acts as a key negative regulator of ciliogenesis in collaboration with CEP97 by capping the mother centriole thereby preventing cilia formation. Also involved in promoting ciliogenesis. May play a role in the assembly of the mother centriole subdistal appendages thereby effecting the fusion of recycling endosomes to basal bodies during cilia formation. Required for correct spindle formation and has a role in regulating cytokinesis and genome stability via cooperation with CALM1 and CETN2.
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