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Anti-BEST3 Polyclonal Antibody - Biotin
Cat: K107066P - Biotin
Summary:
【Product name】:Anti-BEST3 Polyclonal Antibody - Biotin 【Source】:Rabbit
【Isotype】:IgG
【Gene ID】:144453 【Swiss Prot】:Q8N1M1
【Species reactivity】:Human
【Tested applications】:WB ELISA IHC ICC
【Recommended dilution】:WB 1:50-200. ELISA 1:100-1000. IHC 1:20-200. ICC 1:50-200. IF 1:50-200
【Immunogen】:Recombinant protein of human BEST3
【Storage】:Store at -20℃, avoid freeze/thaw cycles.
Background:
BEST3 belongs to the bestrophin family of anion channels, which includes BEST1 (MIM 607854), the gene mutant in vitelliform macular dystrophy (VMD; MIM 153700), and 2 other BEST1-like genes, BEST2 (MIM 607335) and BEST4 (MIM 607336). Bestrophins are transmembrane (TM) proteins that share a homology region containing a high content of aromatic residues, including an invariant arg-phe-pro (RFP) motif. The bestrophin genes share a conserved gene structure, with almost identical sizes of the 8 RFP-TM domain-encoding exons and highly conserved exon-intron boundaries. Each of the 4 bestrophin genes has a unique 3-prime end of variable length
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