Anti-TK Polyclonal Antibody
Cat: K107431P
Summary:
| 【Product name】：Anti-TK Polyclonal Antibody | 【Source】：Rabbit |
| 【Isotype】：IgG | 【Purification】：Affinity purification |
| 【Gene ID】：7083 | 【Swiss Prot】：P04183 |
| 【Tested applications】：WB,IHC | |
| 【Recommended dilution】：WB 1:5000-8000. IHC 1:100-300. | |
| 【Immunogen】：A synthetic peptide of human TK | |
| 【Public Immunogen Range】：180-230/234aa | |
| 【Storage】：Store at -20℃. Avoid freeze/thaw cycles. | |
Background:
The protein encoded by this gene is a cytosolic enzyme that catalyzes the addition of a gamma-phosphate group to thymidine. This creates dTMP and is the first step in the biosynthesis of dTTP, which is one component required for DNA replication. The encoded protein, whose levels fluctuate depending on the cell cycle stage, can act as a low activity dimer or a high activity tetramer. High levels of this protein have been used as a biomarker for diagnosing and categorizing many types of cancers.
Verified picture:
Western blot analysis with TK antibody diluted at 1:6000;Lane: HeLa,293T.
Immunohistochemistry of paraffin-embedded Human prostate cancer with TK antibody diluted at 1:200.
Immunohistochemistry of paraffin-embedded Human thyroid cancer with TK antibody diluted at 1:200.