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Anti-KLK8 Polyclonal Antibody
Cat: K107448P
Summary:
【Product name】:Anti-KLK8 Polyclonal Antibody 【Source】:Rabbit
【Isotype】:IgG 【Purification】:Affinity purification
【Gene ID】:11202 【Swiss Prot】:O60259
【Tested applications】:IHC
【Recommended dilution】:IHC 1:100-300.
【Immunogen】:A synthetic peptide of human KLK8
【Public Immunogen Range】:15-65/260aa
【Storage】:Store at -20℃. Avoid freeze/thaw cycles.
Background:
Kallikreins are a subgroup of serine proteases having diverse physiological functions. Growing evidence suggests that many kallikreins are implicated in carcinogenesis and some have potential as novel cancer and other disease biomarkers. This gene is one of the fifteen kallikrein subfamily members located in tandem in a gene cluster on chromosome 19. The encoded protein may be involved in proteolytic cascade in the skin and may serve as a biomarker for ovarian cancer. Alternate splicing of this gene results in multiple transcript variants encoding different isoforms.
Verified picture:
Immunohistochemistry of paraffin-embedded Human colorectal cancer with KLK8 antibody diluted at 1:200.