Anti-B2M Polyclonal Antibody
Cat: K107449P
Summary:
| 【Product name】：Anti-B2M Polyclonal Antibody | 【Source】：Rabbit |
| 【Isotype】：IgG | 【Purification】：Affinity purification |
| 【Gene ID】：567 | 【Swiss Prot】：P61769 |
| 【Tested applications】：IHC | |
| 【Recommended dilution】：IHC 1:50-200. | |
| 【Immunogen】：A synthetic peptide of human B2M | |
| 【Public Immunogen Range】：65-115/119aa | |
| 【Storage】：Store at -20℃. Avoid freeze/thaw cycles. | |
Background:
Component of the class I major histocompatibility complex (MHC). Involved in the presentation of peptide antigens to the immune system. Exogenously applied M.tuberculosis EsxA or EsxA-EsxB (or EsxA expressed in host) binds B2M and decreases its export to the cell surface (total protein levels do not change), probably leading to defects in class I antigen presentation (PubMed:25356553).
Verified picture:
Immunohistochemistry of paraffin-embedded Human colorectal cancer with B2M antibody diluted at 1:100.
Immunohistochemistry of paraffin-embedded Human liver cancer with B2M antibody diluted at 1:100.